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Brief Report |
Received March 29, 2002; revised June 19, July 17, 2002; accepted July 19, 2002. From the Intervention Research Center for Late-Life Mood Disorders, University of Pittsburgh School of Medicine, Pittsburgh, PA. Address correspondence to Dr. Miller, University of Pittsburgh, 742 Bellefield Towers, Pittsburgh, PA 15213. e-mail: millermd{at}msx.upmc.edu
Objective/METHODS: The authors examined recurrence rates of major depression in elderly subjects with different foci of interpersonal psychotherapy (IPT), who were treated for up to 3 years with either monthly maintenance IPT and pill placebo or with monthly clinical management and pill placebo. RESULTS: Among subjects with an IPT focus on role conflict, a greater proportion of those treated with maintenance-IPT survived for 3 years without recurrence than those treated with placebo/clinical management. Median time to recurrence was 68.9 weeks in IPT-treated patients versus 16.3 weeks for patients in clinical management. Subjects with an IPT focus on abnormal grief or role transition demonstrated no effect differential for maintenance IPT and pill-placebo on recurrence prevention over supportive clinical management and pill-placebo. CONCLUSION: If replicated in a larger sample, these findings have important implications for ongoing case-management decisions.
Key Words: Interpersonal Therapy Depression DrugPlacebo Comparisons
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P. A. Arean Advances in Psychotherapy for Mental Illness in Late Life Am J Geriatr Psychiatry, February 1, 2003; 11(1): 4 - 6. [Full Text] [PDF] |
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